Manchester United are unbeaten in their last 26 away Premier League matches (W17 D9) and a win or draw here would see the Red Devils equal the longest away unbeaten in English top-flight history, set by Arsenal in a 27-game run between April 2003 and September 2004.
In their last league meeting in February, Manchester United inflicted a 9-0 defeat on Southampton, the joint-biggest Premier League victory in history, with the other two games also involving Man Utd and the Saints: Man Utd 9-0 Ipswich in March 1995 and Southampton 0-9 Leicester City in October 2019.
Southampton won four of their last six Premier League matches against Man Utd at the Dell (L2) but have beaten them just once in 13 league meetings at St Mary’s (D4 L8), a 1-0 win in August 2003 with James Beattie scoring the winner. They are winless in 10 home league games against the Red Devils (D4 L6), despite taking the lead in six of those games.
Manchester United have recovered 35 points from losing positions in Premier League games against Southampton, more than any side has against another in the competition’s history. The Red Devils 10 comeback wins against Saints is also the joint most for one side against a specific opponent in the competition (Man Utd also 10 vs Newcastle).
Southampton have won their first home league match of the season in just three of the last 30 seasons (D12 L15), and haven’t done so in any of their nine seasons since returning to the Premier League in 2012-13 (D5 L4).
Manchester United Team News:
France international Raphael Varane, has been training all week after being unveiled at Old Trafford before the Leeds opener.
The classy centre-back could also be in contention for a place, although he was not involved in the friendly with Burnley in midweek.
Jesse Lingard did feature and his goal in the 3-1 win against the Clarets showed he is retaining the form displayed in the earlier friendlies, after now recovering from COVID-19.
Anthony Martial was another of the scorers in the Old Trafford practice match and he is also hoping for a start, although Alex Telles and Marcus Rashford are sidelined.
Dean Henderson is making progress after the effects of COVID-19 while Phil Jones had some first minutes on the pitch on Tuesday as he makes big steps towards recovery from a long-term absence.
Manchester United Predicted Lineup:
De Gea; Wan-Bissaka, Lindelof, Maguire, Shaw; Fred, McTominay; James, Fernandes, Pogba; Greenwood